Gene therapy for Spinal Muscular Atrophy 1

Genetic disorders are hard to cure because they are caused by a defect in the genes of the patient. Gene therapy promises to give patients a second chance by changing their genes. Recently, a new gene-replacement therapy was approved for the Spinal Muscular Atrophy 1, but what does it mean how does it work?

A-T-C-G to F-A-C-E: what are the odds you’d look like that?

Identity, parentage, innocence. These are some of the things that can be determined with even just a small amount of DNA. But what if… we can do more? What if I can infer what you look like without ever having met you, just by looking at your DNA? Scientists strive to do just that.

Can CRISPR-Cas9 gene editing finally allow for pig organ transplantations for humans?

The organs in pigs can be suitable for human transplantation. They are nearly identical to human organs in terms of activity and size. However, every animal’s genome is loaded with integrated viruses. The viruses that are present in pigs are mostly harmless to them, but could lead to tumor growth and defects in the immune system if they were to be passed on to humans. A recent research paper tried to tackle these problems with the use of molecular scissors to edit the viruses out of the pig genome.

91% accuracy! Is deep learning the key to determining effective cancer treatment?

A growing problem doctors face is that the primary cell type that produces cancer is sometimes undetermined. This leaves patients with generalized treatment options and a lower survival chance. However, with the use of neural networks and DNA sequencing, there seems to be hope for identifying these primary sites and providing specialized treatment. But what aspects of the genome gives us the best clues and why might some cancer types be harder to identify?

AlphaFold: Unfolding the mystery behind proteins, the building blocks of life

For generations, biologists have aimed to understand every single process of life. The key to moving closer to this goal is to further understand the compounds that govern almost all life processes, i.e. proteins. AlphaFold, a revolutionary new AI tool holds the potential to give us the power to evaluate protein structures like never before, further breaking barriers for advancements in research as well as medicine.


Something went wrong. Please refresh the page and/or try again.

It’s about sharing

This blog presents the final projects of the students of genomics at the University of Toronto Scarborough.

The Odyssey of Homer is among the oldest stories on Earth. It is a tale of challenge, of learning and of discovery. In this spirit, The Genomic Odyssey was created to explore new ways of discovering and sharing.


Get new content delivered directly to your inbox.